GLIN==> SEMINAR OCT 24 - ANN ARBOR

[Colleen Vogler <clv@umich.edu>]

NOAA GREAT LAKES SEMINAR SERIES
http://www.glerl.noaa.gov/news/seminars/

Date:
Friday, October 24, 2003

Time:
10:30 am

Title:
"BODY RESIDUES: IMPLICATIONS IN ECOTOXICOLOGY AND HAZARD ASSESSMENT"

Speaker:
Dr. Lance J. Schuler
Department of Zoology
Fisheries and Illinois Aquaculture Center
Southern Illinois University
Carbondale, Illinois

Where:
NOAA/GLERL Main Conference Room
2205 Commonwealth Blvd.
Ann Arbor, MI 48105
For directions:
http://www.glerl.noaa.gov/facil/triptik.html

Abstract:
The internal lethal body residue has been 
recognized as a potential dose metric for 
toxicological assessments. This "critical body 
residue" method predicts that the internal lethal 
concentration, for chemicals acting via narcosis, 
is constant at residues ranging from 2 to 8 
µmol*g-1ww. This study was undertaken to evaluate 
if toxicity expressed on a body residue basis, 
contains a temporal component or holds constant 
irrespective of exposure time. In addition to the 
temporal examinations, the influence of lipid 
content, toxicokinetics and biotransformation 
also will be discussed in terms of their 
potential for reducing the variability of the 
lethal residues among test species and chemicals. 
The information collected from this study will 
permit a greater understanding of 
residue-response relationships.

--
Colleen L. Vogler
Administrator
CILER/University of Michigan
401 E. Liberty St., Suite 330
Ann Arbor, MI 48104-2298

Office:	734-764-2426
Fax:	734-647-0768
Email:	clv@umich.edu
Web:	http://www.ciler.org

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