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GLIN==> phthalate ester health effects



Environmentally ubiquitous phthalate esters, used as plasticizing agents in 
polyvynyl chloride and other plastics....a contributor to your "new car smell"....
....and a compound pollutant family that is found extensively throughout the Great Lakes....
....causes birth defects in male children at maternal doses that are below
current EPA toxicology acceptable exposure thresholds:

http://www.ehponline.org/docs/2006/8663/abstract.html

"We estimated the median and 95th percentile of daily exposures to DBP to be 0.99 and 2.68 µg/kg/day, respectively ; for DEP, 6.64 and 112.3 µg/kg/day ; for BBzP, 0.50 and 2.47 µg/kg/day ; and for DEHP, 1.32 and 9.32 µg/kg/day. The U.S. Environmental Protection Agency (EPA) reference doses for these chemicals are 100 (DBP) , 800 (DEP) , 200 (BBzP) , and 20 (DEHP) µg/kg/day. The median and 95th percentile exposure estimates for the phthalates associated with reduced anogenital distance in the study population are substantially lower than current U.S. EPA reference doses for these chemicals and could be informative to any updates of the hazard assessments and risk assessments for these chemicals "

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Alex J. Sagady & Associates        http://www.sagady.com

Environmental Enforcement, Permit/Technical Review, Public Policy, 
Evidence Review and Litigation Investigation on Air, Water and 
Waste/Community Environmental and Resource Protection
Prospectus at:  http://www.sagady.com/sagady.pdf 

657 Spartan Ave,  East Lansing, MI  48823  
(517) 332-6971; (517) 332-8987 (fax); ajs@sagady.com
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