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GLIN==> Upcoming Seminar



Dr. Peter Landrum from the Great Lakes Environmental Research Laboratory, will be giving a seminar on Tuesday January 23, as a part of the NOAA/ University of Michigan Great Lakes Seminar Series.

Please find details of his talk listed below.

Title: Making the connection between exposure and toxic response for aquatic organisms

Speaker: Dr. Peter Landrum, Great Lakes Environmental Research Laboratory

Date: Tuesday January 23

Time: 1030 AM

Location: NOAA/ GLERL
             2205 Commonwealth Blvd., Ann Arbor, MI, 48105

Abstract:
Over the past decade or so, research has advanced to allow better understanding of the connection between the concentrations of contaminants in the external environment and the observed toxicity in aquatic organisms. Toxicity is a time-dose-response relationship based on the concentration of the compound at the receptor site. Thus, the toxic response depends on both the toxicokinetics (uptake, elimination, and biotransformation) and the toxicodynamics (rates of damage formation and damage repair). While most standard toxicity tests, that are the basis for risk assessments, are performed for specific durations, many exposures of aquatic organisms occur through pulsed exposures with differing durations, amplitudes and recovery periods. To better interpret the expected response and to take into account recovery periods, the temporal factors that control the response need to be established. This presentation will provide an overview of the models to establish the relationship between exposure and response, demonstrate the impact of biotransformation on the overall response relationship, and include insights into latent toxicity post exposure for aquatic organisms.


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If you have any questions or concerns, please email me at kanika.suri@noaa.gov; or call 734-741-2147.

For more information about the seminar series, please visit our website at http://www.glerl.noaa.gov/news/seminars/

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Kanika Suri
Web Designer Associate

NOAA Great Lakes Environmental Research Laboratory
2205 Commonwealth Blvd.,
Ann Arbor, MI
48105

Tel: (734) 741-2147
Fax: (734) 741-2055

www.glerl.noaa.gov

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