GLIN==> Upcoming Seminar

[Kanika Suri <Kanika.Suri@noaa.gov>]

Dr. Peter Landrum  from the Great Lakes Environmental Research 
Laboratory, will be giving a seminar on Tuesday January 23, as a part of 
the NOAA/ University of Michigan Great Lakes Seminar Series.

Please find details of his talk listed below.

Title: Making the connection between exposure and toxic response for 
aquatic organisms

Speaker: Dr. Peter Landrum,  Great Lakes Environmental Research Laboratory

Date: Tuesday January 23

Time: 1030 AM

Location: NOAA/ GLERL
             2205 Commonwealth Blvd., Ann Arbor, MI, 48105

Abstract:
Over the past decade or so, research has advanced to allow better 
understanding of the connection between the concentrations of 
contaminants in the external environment and the observed toxicity in 
aquatic organisms. Toxicity is a time-dose-response relationship based 
on the concentration of the compound at the receptor site. Thus, the 
toxic response depends on both the toxicokinetics (uptake, elimination, 
and biotransformation) and the toxicodynamics (rates of damage formation 
and damage repair). While most standard toxicity tests, that are the 
basis for risk assessments, are performed for specific durations, many 
exposures of aquatic organisms occur through pulsed exposures with 
differing durations, amplitudes and recovery periods. To better 
interpret the expected response and to take into account recovery 
periods, the temporal factors that control the response need to be 
established. This presentation will provide an overview of the models to 
establish the relationship between exposure and response, demonstrate 
the impact of biotransformation on the overall response relationship, 
and include insights into latent toxicity post exposure for aquatic 
organisms.

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If you have any questions or concerns, please email me at 
kanika.suri@noaa.gov; or call 734-741-2147.

For more information about the seminar series, please visit our website 
at http://www.glerl.noaa.gov/news/seminars/

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Kanika Suri
Web Designer Associate

NOAA Great Lakes Environmental Research Laboratory
2205 Commonwealth Blvd.,
Ann Arbor, MI
48105

Tel: (734) 741-2147
Fax: (734) 741-2055

www.glerl.noaa.gov

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